Intra-arterial tirofiban in a male nonagenarian with acute ischemic stroke: A case report

Autor: Ding Xianhui, Gu Ao, Yang Qian, Zhou Zhiming, Shi Xiaolei
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Open Life Sciences, Vol 14, Iss 1, Pp 515-518 (2019)
Druh dokumentu: article
ISSN: 2391-5412
DOI: 10.1515/biol-2019-0057
Popis: Nonagenarians with acute ischemic stroke tend to have a higher mortality and morbidity than younger patients. Tirofiban is a glycoprotein IIb/IIIa antagonist that has a therapeutic potential for ischemic stroke. Here, we provide a case report of a 93-year-old male patient with acute ischemic stroke. He presented with right-sided hemiparesis for 2 hours (National Institute of Health Stroke Scale, NIHSS = 23). Immediate treatment with endovascular tirofiban infusion achieved an improvement of intracranial blood flow and a progressively decreased NIHSS one day after admission (NIHSS = 16) and then seven days after admission (NIHSS = 7). After a follow-up of 90 days, the modified ranking score was 2. This case report suggests that endovascular application with tirofiban may be a favorable option for treating nonagenarians presenting with acute ischemic stroke and warrants further study.
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