Quantitative peripheral computed tomography to measure muscle area and assess lean soft tissue mass in children
Autor: | Diana Paola Córdoba-Rodríguez, Iris Iglesia, Alejandro Gomez-Bruton, María L Miguel-Berges, Paloma Flores-Barrantes, José Antonio Casajús, Luis A. Moreno, Gerardo Rodríguez |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Annals of Human Biology, Vol 48, Iss 2, Pp 93-100 (2021) |
Druh dokumentu: | article |
ISSN: | 0301-4460 1464-5033 03014460 |
DOI: | 10.1080/03014460.2021.1877352 |
Popis: | Background Skeletal muscle is one of the main components of lean soft tissue mass (LSTM). Low levels in children affect locomotion, posture, and increase the risk of metabolic syndrome. Aim (1) To evaluate the association between muscle cross-sectional area (MCSA) of the lower left leg measured by peripheral quantitative computed tomography (pQCT) and total LSTM; namely, total left leg and left lower leg LSTM assessed by dual-energy X-ray absorptiometry (DXA) in a group of children, (2) to examine if MCSA is a predictor of LSTM, (3) to determine the ability of pQCT to identify children with low LSTM. Subjects and methods Lower left leg MCSA and LSTM were measured using pQCT and DXA, respectively, in 396 children. Results Statistically significant positive correlations were found between the lower leg MCSA – total LSTM (r² = 0.789), total leg LSTM (r² = 0.79), and lower leg LSTM (r² = 0.791) (p |
Databáze: | Directory of Open Access Journals |
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