Sarcoma of the Ewing Family in Pregnancy: A Case Report of Intrauterine Fetal Death after Induction of Chemotherapy

Autor: S. Schur, J. Wild, G. Amann, W. Köstler, M. Langer, T. Brodowicz
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Case Reports in Oncology, Vol 5, Iss 3, Pp 633-638 (2012)
Druh dokumentu: article
ISSN: 1662-6575
DOI: 10.1159/000345568
Popis: Ewing’s sarcoma is an ultra-orphan disease (2/1,000,000/year) which requires a multimodal therapy approach in high-volume centers. Treatment consists of pre-operative therapy followed by surgery and post-operative combination of chemo-radiotherapy. Experience with diagnosis and therapy of Ewing’s sarcoma in pregnancy is very limited. We herein report the case of an atypical Ewing’s sarcoma detected in the second trimester of gestation. Neoadjuvant chemotherapy was initiated and resulted in substantial tumor shrinkage and intrauterine fetal death. The rare nature of this condition underlines once more the need for a multidisciplinary team to improve the quality of care for this highly special patient collective.
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