| Autor: |
Sakiko Maekawa, Umeharu Ohto, Takuma Shibata, Kensuke Miyake, Toshiyuki Shimizu |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/ncomms11813 |
| Popis: |
NOD2 has a role in host innate immune responses, activating the NF-κB signalling pathway and mutations have been associated with chronic inflammatory disorders. Here, Maekawa et al. solved the structure of NOD2 in its inactive form, suggesting a mechanism for autoinhibition. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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