PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION

Autor:	N. A. Shostak, A. A. Klimenko, N. A. Demidova, I. V. Novikov
Jazyk:	English<br />Russian
Rok vydání:	2016
Předmět:	pulmonary hypertension chronic thromboembolic pulmonary hypertension thromboembolism of pulmonary artery thromboendarterectomy bosentan prostacyclin analogues phosphodiesterase-5 inhibitors Therapeutics. Pharmacology RM1-950 Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Рациональная фармакотерапия в кардиологии, Vol 7, Iss 2, Pp 199-203 (2016)
Druh dokumentu:	article
ISSN:	1819-6446 2225-3653
DOI:	10.20996/1819-6446-2011-7-2-199-203
Popis:	Data about chronic thromboembolic pulmonary hypertension (CTPH) prevalence is presented. The main CTPH clinical manifestations are described. The possible reasons and pathogenetic mechanisms of CTPH development are discussed. Features of unfavorable disease prognosis are also presented. Indications, results, limitations for CTPH surgical treatment are shown. Data of the currently completed clinical studies on bosentan, prostacyclin analogues and phosphodiesterase-5 inhibitors usage in CTPH are presented.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/742081c33a9c4b3692950e06492be280 Zobrazit plný text záznamu View record in DOAJ