Impact of adjuvant chemotherapy on the survival of patients with breast cancer diagnosed by screening

Autor: Irene Zarcos‐Pedrinaci, Maximino Redondo, Javier Louro, Francisco Rivas‐Ruiz, Teresa Téllez, Diego Pérez, Francisco Medina Cano, Kenza Machan, Laia Domingo, Maria Mar Vernet, Maria Padilla‐Ruiz, Xavier Castells, Antonio Rueda, María Sala, REDISSEC‐CaMISS Group
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Cancer Medicine, Vol 8, Iss 15, Pp 6662-6670 (2019)
Druh dokumentu: article
ISSN: 2045-7634
DOI: 10.1002/cam4.2488
Popis: Abstract The aim of this study is to determine the survival of patients with breast cancer treated with adjuvant chemotherapy (ACh) after the diagnosis by screening, taking comorbidity into account. This multicenter cohort study examined a population of patients taking part in four national screening programs for the early detection of breast cancer (localized or locally advanced), during the period 2000‐2008. Of the 1248 cancers detected, 266 were prevalent (21.3%), 633 were incident (50.7%), and 349 were interval (27.9%). No significant differences were detected between the three groups in terms of the distribution of comorbidity according to the CCI. After a median follow‐up of 102 months, 22.1% of the patients with interval cancer had died. The corresponding figures for the incident and prevalent cancers were 10.4% and 7.9%, respectively (P
Databáze: Directory of Open Access Journals
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