Diagnostic and prognostic value of heparin-binding protein in pediatric community-acquired pneumonia

Autor: Samah Abdelghany Mohamed, Rehab Elmeazawy, Radwa El Sharaby, Ahmed Abdel Razik
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Egyptian Pediatric Association Gazette, Vol 72, Iss 1, Pp 1-8 (2024)
Druh dokumentu: article
ISSN: 2090-9942
DOI: 10.1186/s43054-024-00325-8
Popis: Abstract Background Community-acquired pneumonia (CAP) and its associated complications pose a noteworthy public health apprehension in the pediatric population, leading to considerable morbidity and mortality. The objective of this study was to assess the diagnostic and prognostic value of heparin-binding protein (HBP) as a promising biomarker in children hospitalized with CAP. Methods This prospective, single-center study included 50 children admitted to the Pediatric Pulmonology Unit between April 2023 and January 2024 with a diagnosis of CAP, as well as age-matched 50 healthy children as a control group. Demographic, clinical, and laboratory data were recorded. The measurement of serum HBP was conducted upon admission utilizing the enzyme-linked immunosorbent assay technique. Results Serum HBP was elevated in the CAP group in comparison to the control group (p
Databáze: Directory of Open Access Journals
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