| Autor: |
Magdalena Naumovska, Aboma Merdasa, Björn Hammar, John Albinsson, Ulf Dahlstrand, Magnus Cinthio, Rafi Sheikh, Malin Malmsjö |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Photoacoustics, Vol 27, Iss , Pp 100384- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2213-5979 |
| DOI: |
10.1016/j.pacs.2022.100384 |
| Popis: |
Photoacoustic (PA) imaging is rapidly emerging as a promising clinical diagnostic tool. One of the main applications of PA imaging is to image vascular networks in humans. This relies on the signal obtained from oxygenated and deoxygenated hemoglobin, which limits imaging of the vessel wall itself. Giant cell arteritis (GCA) is a treatable, but potentially sight- and life-threatening disease, in which the artery wall is infiltrated by leukocytes. Early intervention can prevent complications making prompt diagnosis of importance. Temporal artery biopsy is the gold standard for diagnosing GCA. We present an approach to imaging the temporal artery using multispectral PA imaging. Employing minimally supervised spectral analysis, we produce histology-like images where the artery wall is clearly discernible from the lumen and further differentiate between PA spectra from biopsies diagnosed as GCA- and GCA+ in 77 patients. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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