Acute Aortic Dissection in Young Adult Patients: Clinical Characteristics, Management, and Perioperative Outcomes

Autor: Shuai Zhu, Tie Zheng, Zhi-Yu Qiao, Li Chen, Jia-Fu Ou, Wei-Gang Fang, Cheng-Nan Li, Lei Chen, Wei-Guo Ma, Jun Zheng, Yong-Min Liu, Li-Zhong Sun, Xue-Jun Sun, Jun-Ming Zhu
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Investigative Surgery, Vol 33, Iss 3, Pp 211-217 (2020)
Druh dokumentu: article
ISSN: 0894-1939
1521-0553
08941939
DOI: 10.1080/08941939.2018.1489916
Popis: Background: Acute aorta dissection (AD) is a fatal emergency, however, studies addressing the clinical characteristics, management, and outcome of acute AD in young adult patients aged under 45 years in China are very few. Methods: A retrospective study including 490 patients with acute AD as the final diagnosis was conducted. Patients’ demographics, clinical characteristics, medical history, and laboratory and diagnostic imaging findings were retrieved from medical records. Results: The median age of young adult patients with acute AD was 38 years old with an interquartile range from 33 to 41. Male and smoker constituted 84.49% and 50.61% of the cohort, respectively. Hypertension was found in 54.49%, while Marfan syndrome was seen in 4.29% of the patients. Abrupt onset of chest or back pain was the most common symptoms (85.31%), while altered consciousness, coma and oliguria were less reported. Most patients (89.39%) were managed with surgical interventions. Typical complications (central nervous system complications, spinal cord ischemia, myocardial ischemia/infarction, mesenteric ischemia/infarction and acute renal failure) were seen in a small portion of treated patients during perioperative period. For in-hospital mortality there were 24 (∼5%) cases recorded. Correlation analysis indicated that perioperative complications were associated with the length of cardiopulmonary bypass (CPB) (P
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