Desferrioxamine-related ocular toxicity: A case report

Autor: Sumu Simon, Paul A Athanasiov, Rajeev Jain, Grant Raymond, Jagjit S Gilhotra
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Apoptosis
glaucoma
intraocular pressure
retinal ganglion cells
retinal ischemia
tumor necrosis factor-alpha
Branch retinal vein occlusion
laser
Lucentis
macular edema
Microbial etiology
mucopurulent keratitis
suppurative keratitis
Intraoperative application of mitomycin C
mitomycin C
postoperative complications
preoperative subconjunctival injection
recurrence rate
recurrent pterygium
Cataract
inflammation
mydriasis
prevention and control
surgery
Cross-cylinder technique
photoastigmatic refractive keratectomy
refractive surgery
′BARC I-125 Ocu-Prosta seeds′
choroidal melanoma
plaque brachytherapy
retinoblastoma
vasoproliferative tumors
Asian Indian
Amaurosis
amaurosis hemianopia
capsulolenticular cataract
conjunctiva
lenticular cataract
leukoma
eye lid
ophthalmia chronica
ophthalmic purulentis
Interpretation
magnetic resonance imaging
orbit
ophthalmology
Antivascular endothelial growth factor
intravitreal bevacizumab
ocular inflammation
Acute macular neuroretinopathy
optical coherence tomography
scotoma
Desferrioxamine
ocular toxicity
optic neuropathy
pigmentary retinopathy
Ophthalmology
RE1-994
Zdroj: Indian Journal of Ophthalmology, Vol 60, Iss 4, Pp 315-317 (2012)
Druh dokumentu: article
ISSN: 0301-4738
1998-3689
DOI: 10.4103/0301-4738.98714
Popis: A 29-year-old lady receiving repeated blood transfusions for β thalassemia since childhood, presented with rapidly deteriorating symptoms of night blindness and peripheral visual field loss. She was recently commenced on high-dose intravenous desferrioxamine for reducing the systemic iron overload. Clinical and investigative findings were consistent with desferrioxamine-related pigmentary retinopathy and optic neuropathy. Recovery was partial following cessation of desferrioxamine. This report highlights the ocular side-effects of desferrioxamine mesylate and the need to be vigilant in patients on high doses of desferrioxamine.
Databáze: Directory of Open Access Journals
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