| Autor: |
Agustina Martinez Garmendia, Maria Nelly Gutierrez Acevedo, Sabrina Barbero, Lorena del Carmen Notari, Marina Agozino, Jose Luis Fernandez, Maria Margarita Anders, Nadia Grigera, Florencia Antinucci, Orlando Orozco Ganem, Maria Dolores Murga, Daniea Perez, Ana Palazzo, Liria Martinez Rejtman, Ivonne Giselle Duarte, Julio Vorobioff, Victoria Trevizan, Sofía Bulaty, Fernando Bessone, José Daniel Bosia, Silvia Mabel Borzi, Teodoro E. Stieben, Adriano Masola, Sebastian Eduardo Ferretti, Diego Arufe, Ezequiel Demirdjian, Maria Pia Raffa, Cintia Elizabet Vazquez, Pablo Ruiz, José Emanuel Martínez, Hugo Fainboim, Mirta Peralta, Leandro Alfredo Heffner, Andrea Odzak, Melisa Dirchwolf, Astrid Smud, Manuel Mendizabal, Carla Bellizzi, Diego Giunta, Marcelo Valverde, Martin Elizondo, Ezequiel Mauro, Ana Martinez, Jesica Tomatis, Andres Bruno, Agñel Ramos, Josefina Pages, Silvina Tevez, Salvatore Piano, Adrian Gadano, Sebastián Marciano |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Annals of Hepatology, Vol 24, Iss , Pp 100496- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1665-2681 |
| DOI: |
10.1016/j.aohep.2021.100496 |
| Popis: |
Background: Predicting short-term mortality in patients with cirrhosis and bacterial infections is challenging. Aims: To compare the performance of various scores in predicting in-hospital mortality in this population. Methods: We performed an analysis of the multicenter prospective cohort study of patients with cirrhosis with bacterial infections throughout Argentina and Uruguay (clinicatrials.gov.NCT03919032). Patients were classified according to the CLIF criteria as having ACLF or mere acute decompensation (AD). We evaluated the performance of scores of liver disease and infection severity in predicting in-hospital mortality. MELD, MELD-Na, and Quick SOFA (qSOFA) were computed in all patients. CLIF-AD was only computed in patients without ACLF, and CLIF-ACLF only in patients with ACLF. We plotted ROC curves and estimated their area under the curve (AUROC). Results: We included 472 patients: 66% male, mean age 57 ± 12 years. Most frequent infections: SBP (30%) and urinary tract infection (25%). Overall, 332 (70%) patients had acute decompensation, and 140 (30%) ACLF. In-hospital mortality rate was 19%: 41% in patients with ACLF vs 10% in patients with AD (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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