Staphylococcus lugdunensis Endophthalmitis: Case Series and Literature Review

Autor: Kuan-Jen Chen, Ming-Hui Sun, Andrew S. H. Tsai, Chi-Chin Sun, Wei-Chi Wu, Chi-Chun Lai
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Antibiotics, Vol 11, Iss 11, p 1485 (2022)
Druh dokumentu: article
ISSN: 2079-6382
DOI: 10.3390/antibiotics11111485
Popis: Staphylococcus lugdunensis endophthalmitis is an uncommon intraocular infection with potentially visually devastating consequences. S. lugdunensis endophthalmitis have been reported following cataract surgery, trauma, intravitreal injections of anti-vascular endothelial growth factor agents and dexamethasone implant. We report four cases of postoperative S. lugdunensis endophthalmitis after cataract extraction (three patients) and combined pars plana vitrectomy and cataract extraction (one patient). The onset of presentation of endophthalmitis was acute (within 2 weeks) in two patients, subacute (2 to 6 weeks) in one patient, and chronic (more than 6 weeks) in one patient. All patients had presenting visual acuity (VA) of hand motions or worse and were treated with pars plana vitrectomy with intravitreal antibiotics. The final VA was 20/50 in two patients, 4/200 in one patient with pre-existing myopic maculopathy, and no light perception in one patient with retinal detachment. In antibiotic susceptibility testing, S. lugdunensis isolates were resistant to penicillin (3/4, 75%), but all were susceptible to vancomycin, oxacillin, teicoplanin, tigecycline, and sulfamethoxazole-trimethoprim. S. lugdunensis may be associated with acute or chronic endophthalmitis. Favorable visual outcomes can be achieved with prompt diagnosis and management.
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