Efficacy of 308-nm excimer laser combined with fractional CO2 laser in treatment of stable vitiligo

Autor: Ya-nan KE, Yong YU, Xiu-ling SHEN, Kun-xia YANG, Ya-ping TANG, Zhen-jie LI
Jazyk: čínština
Rok vydání: 2020
Předmět:
Zdroj: Pifu-xingbing zhenliaoxue zazhi, Vol 27, Iss 1, Pp 19-22 (2020)
Druh dokumentu: article
ISSN: 1674-8468
DOI: 10.3969/j.issn.1674-8468.2020.01.005
Popis: Objective: To evaluate the efficacy and safety of fractional CO2 laser combined with 308-nm excimer laser for the treatment of stable vitiligo. Methods: A total of 118 patients of stable vitiligo were enrolled in this trial. Patients were assigned into the treatment group (n=59, 328 lesions) and control group (n=59, 319 lesions) using a random digital table method. The treatment group was treated with fractional CO2 laser combined with 308-nm excimer laser, while the control group was treated with 308-nm excimer laser alone. Efficacy and adverse reactions were evaluated after 3 months of consecutive treatments. Results: After the treatments, the total effective rates were higher in the treatment group than that in the control group (89.94% vs. 84.64%, χ2=6.59, P=0.014). The rate of the adverse reactions did not differ between the two groups (23.34% vs. 22.15%, χ2=1.29, P=0.088). Conclusion: 308-nm excimer laser combined with fractional CO2 laser is safe and effective for patients with stable vitiligo.
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