Body fat distribution: the answer to the apparent paradox of obesity in cardiology?

Autor: Daria A. Borodkina, Olga V. Gruzdeva, Ludmila V. Kvitkova, Olga L. Barbarash
Jazyk: English<br />Russian
Rok vydání: 2017
Předmět:
Zdroj: Ожирение и метаболизм, Vol 14, Iss 2, Pp 3-8 (2017)
Druh dokumentu: article
ISSN: 2071-8713
2306-5524
DOI: 10.14341/omet201723-8
Popis: Today, despite all the measures taken, cardiovascular diseases remain the main cause of temporary invalidization, disability and mortality. Obesity is a major risk factor of cardiovascular diseases and complications from them. However, not all fat depots have the same proinflammatory, paracrine and metabolic activity. Recent studies have shown that the accumulation of visceral fat, and not subcutaneous fat, is associated with an increase in cardiometabolic risk. At the same time, there is evidence that an increase in the area of visceral fat is a protective mechanism against lipotoxicity. The purpose of this review is to discuss current literature data reflecting the characteristics of the visceral, epicardial and perivascular fat depots, and also their association with cardiovascular diseases.
Databáze: Directory of Open Access Journals