Ultrasound-Mediated Cavitation of Magnetic Nanoparticles for Drug Delivery Applications

Autor:	Huber Christian, George Benedikt, Rupitsch Stefan J., Ermert Helmut, Ullmann Ingrid, Vossiek Martin, Lyer Stefan
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	ultrasound cavitation magnetic nanoparticles drug delivery sonosensitivity Medicine
Zdroj:	Current Directions in Biomedical Engineering, Vol 8, Iss 2, Pp 568-571 (2022)
Druh dokumentu:	article
ISSN:	2364-5504 33035202
DOI:	10.1515/cdbme-2022-1145
Popis:	Magnetic nanoparticles guided by an external magnetic field can be used to deliver drugs (e.g., chemotherapeutics) to malignant regions (e.g., tumor tissue). Some nonmagnetic, sonosensitive nanoparticles are known to generate cavitation induced by focused ultrasound. This can can be used to monitor spatial/temporal particle distribution and to stimulate local drug release in target regions. Little to nothing is known about the sonosensitivity of magnetic nanoparticles. Therefore, we investigated this physical phenomenon in the present contribution. We showed that certain magnetic nanoparticles have high cavitation potential and are promising for further research in this regard.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/738c3303520244c5b543729200f3ba76 Zobrazit plný text záznamu View record in DOAJ