Esophageal Carcinosarcoma in a Patient with Corrosive Esophagitis

Autor: Young Ki Kim, Okran Shin, Sung Soo Kim
Jazyk: English<br />Korean
Rok vydání: 2020
Předmět:
Zdroj: The Korean Journal of Helicobacter and Upper Gastrointestinal Research, Vol 20, Iss 3, Pp 233-236 (2020)
Druh dokumentu: article
ISSN: 1738-3331
DOI: 10.7704/kjhugr.2020.0017
Popis: Esophageal carcinosarcoma is a rare type of esophageal cancer characterized by both carcinomatous and sarcomatous components. Its endophytic growth tendency into the esophageal lumen leads to a higher curative resection rate. However, lymph node metastases in esophageal carcinosarcoma occur at a relatively early stage. We report a case of esophageal carcinosarcoma in a 52-year-old man who had dysphagia for 2 months and a history of ingestion of glacial acetic acid in adolescence. His endoscopy and chest CT results showed an 8.5-cm-sized ulcerative polypoid mass with multiple lymph node metastases in the mid-esophagus. Biopsy revealed an interweaving spindle cell proliferation with squamous dysplasia. Immunohistochemical staining showed positive expressions of vimentin and cytokeratin. Even though the patient received concomitant chemoradiotherapy with a stent insertion, he died 7 months after diagnosis. We herein present a case of corrosive esophagitis followed by esophageal carcinosarcoma that suggested the possibility of an association between the two diseases.
Databáze: Directory of Open Access Journals