Effect of magnesium sulfate on bleeding time in pregnancy
| Autor: | Khakbazan Z, Alishirzad A, Mirnateghie A, Babaei Gh, khakbazan M |
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| Jazyk: | perština |
| Rok vydání: | 2005 |
| Předmět: | |
| Zdroj: | حیات, Vol 11, Iss 1-2, Pp 71-78 (2005) |
| Druh dokumentu: | article |
| ISSN: | 1735-2215 2008-188X |
| Popis: | Introduction: According to some studies, pharmacological concentrations of Mg2+ have anti-thrombotic effects and interfere with platelet aggregation in vitro and in vivo. Materials and Methods: The study group consisted of 50 pregnant women who required magnesium sulfate for mild pre-eclampsia or preterm labor. In all patients, a platelet count, magnesium level, bleeding time and mean arterial pressure were obtained before and 2 hours after magnesium sulfate infusion. Magnesium sulfate was started with a 6 gr intravenous bolus, followed by 2 gr/hr infusion. Bleeding time was measured by Duke method. Data were analyzed with Mann Whitney U and Wilcoxon rank tests. Results: Thirty one patients (62%) received magnesium sulfate for preterm labor and 19 (38%) for mild pre-eclampsia. Analysis of the entire study group revealed a rise in the magnesium level (p |
| Databáze: | Directory of Open Access Journals |
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