A ciliated adenocarcinoma of the lung mimicking lung abscess and pneumonia

Autor: Naoki Fujimoto, Kohei Fujita, Ayami Ishida, Koki Moriyoshi, Kiminobu Tanizawa
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Respirology Case Reports, Vol 12, Iss 6, Pp n/a-n/a (2024)
Druh dokumentu: article
ISSN: 2051-3380
98386344
DOI: 10.1002/rcr2.1407
Popis: Abstract This case report describes a 78‐year‐old man initially treated for pneumonia and lung abscess who was resistant to antimicrobial treatment and was eventually diagnosed with ciliated adenocarcinoma. Ciliated adenocarcinoma, a rare non‐terminal respiratory unit (TRU)‐type lung adenocarcinoma, presents a unique diagnostic challenge because of its similarity to pneumonia and lung abscesses. Morphologically, the ciliated adenocarcinoma in this case appeared to be a non‐TRU type adenocarcinoma, with partial mucous epithelium, no visible extracellular mucus, thyroid transcription factor (TTF)‐1 negativity, and mucin (MUC) 5AC positivity on immunostaining. The patient was considered to have ciliated adenocarcinoma based on the fact that the mucous epithelium was partial and extracellular mucus was not prominent. This case emphasizes the importance of considering malignancy in patients with non‐resolving pulmonary infections.
Databáze: Directory of Open Access Journals
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