An Emerging Screening Method for Interrogating Human Brain Function: Tutorial

Autor: Gustavo Sudre, Anto I Bagić, James T Becker, John P Ford
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: JMIR Formative Research, Vol 7, p e37269 (2023)
Druh dokumentu: article
ISSN: 2561-326X
DOI: 10.2196/37269
Popis: Cognitive decline can be observed due to a myriad of causes. Clinicians would benefit from a noninvasive quantitative tool to screen and monitor brain function based on direct measures of neural features. In this study, we used neuroimaging data from magnetoencephalography (with a whole-head Elekta Neuromag 306 sensor system) to derive a set of features that strongly correlate with brain function. We propose that simple signal characteristics related to peak variability, timing, and abundance can be used by clinicians as a screening tool to investigate cognitive function in at-risk individuals. Using a minimalistic set of features, we were able to perfectly distinguish between participants with normative and nonnormative brain function, and we were also able to successfully predict participants’ Mini-Mental Test score (r=0.99; P
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