Immune profile of healthcare professionals six months after vaccination or exposure to SARS‐CoV‐2 in Angola

Autor: Cruz S. Sebastião, Euclides Sacomboio, Ngiambudulu M. Francisco, Edson K. Cassinela, António Mateus, Zinga David, Joana Paixão, Jocelyne Neto de Vasconcelos, Joana Morais
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Health Science Reports, Vol 6, Iss 1, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2398-8835
73603899
DOI: 10.1002/hsr2.1058
Popis: Abstract Background and Aims Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection is a public health concern. Until 2021, more than 2 million cumulative deaths were reported worldwide. Herein, we investigated the immune profile of healthcare professionals 6 months after vaccination or exposure to SARS‐CoV‐2 in Angola. Methods This was a prospective study conducted with 1068 Angolan healthcare professionals between August and December 2021. Participants were screened for the presence of IgG and IgM against SARS‐CoV‐2. Results About 9.6% and 98.2% of the participants had prior exposure to SARS‐CoV‐2 or vaccination against it, respectively. Participants aged between 20 and 40 years (11.2%), female (12.4%), with higher educational level (12.8%), from Luanda (60.3%), and nonhealthcare professionals (8.1%) were the most affected by the SARS‐CoV‐2. Gender, education, and local residence were related to SARS‐CoV‐2 exposure (p 3 months. Individuals who received only the first dose regardless of the type of vaccine had a higher immunity duration (>3 months) than those who received two doses. For individuals who received the Sputnik and Johnson, the average immunity was lower (
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