An efficient green synthesis of novel 1H-imidazo[1,2-a]imidazole-3-amine and imidazo[2,1-c][1,2,4]triazole-5-amine derivatives via Strecker reaction under controlled microwave heating

Autor: Sadek Kamal Usef, Abdel-Hameed Afaf Mohamed, Abdelnabi Hisham A., Meleigy Yasser
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Green Processing and Synthesis, Vol 8, Iss 1, Pp 297-301 (2019)
Druh dokumentu: article
ISSN: 2191-9550
DOI: 10.1515/gps-2018-0093
Popis: A highly efficient multi-component one-pot synthesis of novel 1H-imidazo[1,2-a]imidazole-3-amine and imidazo[2,1-c][1,2,4]triazole-5-amine derivatives has been developed through the reaction of easily available aromatic aldehydes, benzoyl cyanide and either 2-aminoimidazole-4,5-dicarbonitrile or 3-amino-1,2,4-triazole in pyridine under controlled microwave heating. The process is environmentally friendly, is operationally simple, with short reaction time and with high yields.
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