Emerging Systemic Therapies in Advanced Unresectable Biliary Tract Cancer: Review and Canadian Perspective

Autor:	Vincent C. Tam, Ravi Ramjeesingh, Ronald Burkes, Eric M. Yoshida, Sarah Doucette, Howard J. Lim
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	biliary tract cancer rare disease chemotherapy immunotherapy targeted therapy drug access Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Current Oncology, Vol 29, Iss 10, Pp 7072-7085 (2022)
Druh dokumentu:	article
ISSN:	1718-7729 1198-0052
DOI:	10.3390/curroncol29100555
Popis:	Biliary tract cancer (BTC) is a group of rare and aggressive malignancies with a dismal prognosis. There is currently a significant lack in effective treatment options for BTC, with gemcitabine-cisplatin remaining the first-line standard of care treatment for over a decade. A wave of investigational therapies, including new chemotherapy combinations, immunotherapy, and biomarker-driven targeted therapy have demonstrated promising results in BTC, and there is hope for many of these therapies to be incorporated into the Canadian treatment landscape in the near future. This review discusses the emerging therapies under investigation for BTC and provides a perspective on how they may fit into Canadian practice, with a focus on the barriers to treatment access.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/c735cb9d60984c4192f079cf2016bd9c Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.