Glyoxalase biochemistry
| Autor: | Honek John F. |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Biomolecular Concepts, Vol 6, Iss 5-6, Pp 401-414 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1868-5021 1868-503X |
| DOI: | 10.1515/bmc-2015-0025 |
| Popis: | The glyoxalase enzyme system utilizes intracellular thiols such as glutathione to convert α-ketoaldehydes, such as methylglyoxal, into D-hydroxyacids. This overview discusses several main aspects of the glyoxalase system and its likely function in the cell. The control of methylglyoxal levels in the cell is an important biochemical imperative and high levels have been associated with major medical symptoms that relate to this metabolite’s capability to covalently modify proteins, lipids and nucleic acid. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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