Sickle cell trait: a cause of abdominal pain and pulmonary embolism
| Autor: | Emanuel José Saad, Ayelén Tarditi Barra, Gabriela Monzoni, Carolina Villegas, Aldo Hugo Tabares |
|---|---|
| Jazyk: | English<br />Spanish; Castilian<br />Portuguese |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Revista de la Facultad de Ciencias Médicas de Córdoba, Vol 77, Iss 4 (2020) |
| Druh dokumentu: | article |
| ISSN: | 0014-6722 1853-0605 |
| DOI: | 10.31053/1853.0605.v77.n4.25077 |
| Popis: | Introduction: Sickle cell trait (SCT) is a rare and underdiagnosed disorder in the Argentinian population. In this condition, individuals carry the mutation of the HbS gene in one of the two beta-globin genes. In general, SCT does not present with the typical manifestations of sickle cell anemia. However, under certain circumstances, some clinical characteristics of the disease may develop. Methods: We discussed the case of a 39-Year old man who presented with persistent abdominal pain of unknown origin after traveling to a high-altitude place. He underwent laparotomy without a definite diagnosis. After that, the patient developed signs of splenic infarction and pulmonary thromboembolism that were confirmed by computed tomography. Results: A sickling test was positive, and a hemoglobin electrophoresis revealed an abnormal fraction at the HbS level. In this context a diagnosis of SCT was made. Additional, tests revealed a strongly positive lupus anticoagulant. Conclusion: SCT presentation as abdominal pain and thromboembolic disease in adult patients after exposure to high altitudes is a rarely suspected diagnosis. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|