Neuronavigated Versus Non-navigated Repetitive Transcranial Magnetic Stimulation for Chronic Tinnitus: A Randomized Study

Autor: Hanna Sahlsten, Anu Holm, Esa Rauhala, Mari Takala, Eliisa Löyttyniemi, Max Karukivi, Johanna Nikkilä, Kirsi Ylitalo, Janika Paavola, Reijo Johansson, Tero Taiminen, Satu K. Jääskeläinen
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Trends in Hearing, Vol 23 (2019)
Druh dokumentu: article
ISSN: 2331-2165
23312165
DOI: 10.1177/2331216518822198
Popis: Repetitive transcranial magnetic stimulation (rTMS) has shown variable effect on tinnitus. A prospective, randomized 6-month follow-up study on parallel groups was conducted to compare the effects of neuronavigated rTMS to non-navigated rTMS in chronic tinnitus. Forty patients (20 men, 20 women), mean age of 52.9 years (standard deviation [ SD ] = 11.7), with a mean tinnitus duration of 5.8 years ( SD = 3.2) and a mean tinnitus intensity of 62.2/100 ( SD = 12.8) on Visual Analog Scale (VAS 0–100) participated. Patients received 10 sessions of 1-Hz rTMS to the left temporal area overlying auditory cortex with or without neuronavigation. The main outcome measures were VAS scores for tinnitus intensity, annoyance, and distress, and Tinnitus Handicap Inventory (THI) immediately and at 1, 3, and 6 months after treatment. The mean tinnitus intensity (hierarchical linear mixed model: F 3 = 7.34, p = .0006), annoyance ( F 3 = 4.45, p = .0093), distress ( F 3 = 5.04, p = .0051), and THI scores ( F 4 = 17.30, p
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