Development of Flexible Ion-Selective Electrodes for Saliva Sodium Detection

Autor: Hyo-Ryoung Lim, Soon Min Lee, Musa Mahmood, Shinjae Kwon, Yun-Soung Kim, Yongkuk Lee, Woon-Hong Yeo
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Sensors, Vol 21, Iss 5, p 1642 (2021)
Druh dokumentu: article
ISSN: 1424-8220
DOI: 10.3390/s21051642
Popis: Saliva can be used for health monitoring with non-invasive wearable systems. Such devices, including electrochemical sensors, may provide a safe, fast, and cost-efficient way of detecting target ions. Although salivary ions are known to reflect those in blood, no available clinical device can detect essential ions directly from saliva. Here, we introduce an all-solid-state, flexible film sensor that allows highly accurate detection of sodium levels in saliva, comparable to those in blood. The wireless film sensor system can successfully measure sodium ions from a small volume of infants’ saliva (−5 ≈ 1 M with a low detection limit of 4.27 × 10−5 M. The simultaneous comparison between the film sensor and a commercial electrochemical sensor demonstrates the accuracy of the flexible sensor and a positive correlation in saliva-to-blood sodium levels. Collectively, the presented study shows the potential of the wireless ion-selective sensor system for a non-invasive, early disease diagnosis with saliva.
Databáze: Directory of Open Access Journals
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