Balanced Chromosomal Translocation of Chromosomes 6 and 7: A Rare Male Factor of Spontaneous Abortions

Autor:	Sefa Resim, Erkan Efe, Ateş Kadıoğlu, Tolga Akman, Ayşe Gül Bayrak
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Balanced chromosomal translocation spontaneous abortions preimplantation genetic diagnosis Medicine
Zdroj:	Balkan Medical Journal, Vol 30, Iss 2, Pp 250-252 (2013)
Druh dokumentu:	article
ISSN:	2146-3123 2146-3131
DOI:	10.5152/balkanmedj.2012.107
Popis:	Background: Carriers of structural chromosomal rearrangements such as Robertsonian or reciprocal translocations have an increased risk of spontaneous abortion and producing offspring with genetic abnormalities. Case Report: We report a man with balanced chromosomal translocations located at 6p22, and 7q22. His wife has a history of four spontaneous abortions. Conclusion: Couples with a history of abortions should be investigated cytogenetically, after other causes of miscarriages are excluded. The possibility of spontaneous abortions can be reduced with preimplantation genetic diagnosis (PGD) before embryo transfer.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/732f7c400fc646df8ebbe4d9c4a7e526 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF