10-Year oncological outcome report after second conservative treatment for ipsilateral breast tumor event

Autor: Jean-Michel Hannoun-Levi, Jocelyn Gal, Renaud Schiappa, Marie-Eve Chand
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Clinical and Translational Radiation Oncology, Vol 38, Iss , Pp 71-76 (2023)
Druh dokumentu: article
ISSN: 2405-6308
DOI: 10.1016/j.ctro.2022.10.008
Popis: Purpose: To analyze long-term oncological outcome after 2nd conservative treatment (2ndCT) for patients with ipsilateral 2nd ipsilateral breast tumor event (2ndIBTE). Materials/methods: In this retrospective observational study (N°F20210402152843), patients with 2ndIBTE underwent 2ndCT (lumpectomy + tumor bed re-irradiation). 3rdIBTE (3rdIBTE-FS), regional relapse- (RRFS) and metastatic disease- (MD-FS) free survivals as well as disease-free (DFS), specific (SS) and overall (OS) survival were analyzed. Late toxicity was reported. Results: Between 09/2000 and 04/2022, 244 patients presented a 2ndIBTE and underwent a 2ndCT. Among them, 113 pts with a minimum follow-up of 60 months were analyzed. Median time interval between 1st and 2ndIBTE was 13.5 years [2–35]. Median 2ndIBTE age was 66.2 years [31–85]. 2ndIBTE were adenocarcinomas (77 %). Tumor size was
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