Acute postoperative pain relief, by intraperitoneal application of local anesthetics, during laparoscopic cholecystectomy
| Autor: | Ljiljana Gvozdenović, Vesna Pajtić, Dejan Ivanov, Radovan Cvijanović, Sava Gavrilović, Zoran Gojković, Saša Milić |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Journal of Health Sciences, Vol 1, Iss 2 (2011) |
| Druh dokumentu: | article |
| ISSN: | 2232-7576 1986-8049 |
| DOI: | 10.17532/jhsci.2011.120 |
| Popis: | Introduction: Intraperitoneal administration of local anesthetic in combination with an opioid, for the relief of postoperative pain, has already been reported after laparoscopic cholecystectomy. This study aimed to assess the analgesic effect of the intraperitoneal administration of bupivacaine and morphine, in patients undergoing laparoscopic cholecystectomy. Methods: 90 patients (30 patients in each group) were included in a double blind, randomized manner. At the end of laparoscopic cholecystectomy, the patients were intraperitoneally treated with 30 ml of: physiological saline (Group 1) or 0.25% bupivacaine (Group 2) or 0.25% bupivacaine + 2 mg morphine (Group 3). Patient’s postoperative pain was evaluated using a visual analogue scale and a verbal rating score. The postoperative analgesic requirement was assessed by the total dose of Ketorolak, administered by intravenous or intramuscular route. Pain, vital signs, supplemental analgesics consumption and side effects were recorded for all patients for 12h. Results: There were no difference between the three groups, regarding pain scores (et rest and coughing) during the study, except in the fi rst 6 h, when scores were lower for patients receiving intraperitoneal bipuvacaine + morphine (p |
| Databáze: | Directory of Open Access Journals |
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