| Autor: |
Tatsuo Kanda, Masami Shinozaki, Hidehiro Kamezaki, Shuang Wu, Shingo Nakamoto, Makoto Arai, Keiichi Fujiwara, Nobuaki Goto, Fumio Imazeki, Osamu Yokosuka |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
International Journal of Medical Sciences, Vol 9, Iss 1, Pp 27-32 (2012) |
| Druh dokumentu: |
article |
| ISSN: |
1449-1907 |
| Popis: |
Background/Aims: Spontaneous acute exacerbation of chronic hepatitis B virus (HBV) infection occasionally occurs in its natural history, sometimes leading rapidly to fatal hepatic failure. We compared the effects of lamivudine (LAM) with those of entecavir (ETV) treatments in acute exacerbation of chronic hepatitis B with 500 IU/L or higher alanine aminotransferase (ALT) levels.Methods: Thirty-four patients with acute exacerbation were consecutively treated with LAM /ETV. Their clinical improvements were compared.Results: Among LAM-treated and ETV-treated patients, none showed a reduction of Conclusions: ETV appears to be as effective as LAM in the treatment of patients with acute exacerbation of chronic hepatitis B. Clinicians should carefully start to treat these patients as soon as possible. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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