Elderly versus younger patients with hereditary angioedema type I/II: patient characteristics and safety analysis from the Icatibant Outcome Survey

Autor:	Anette Bygum, Teresa Caballero, Anete S. Grumach, Hilary J. Longhurst, Laurence Bouillet, Werner Aberer, Andrea Zanichelli, Jaco Botha, Irmgard Andresen, Marcus Maurer, for the IOS Study Group
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Hereditary angioedema Icatibant Outcome Survey Safety Elderly Immunologic diseases. Allergy RC581-607
Zdroj:	Clinical and Translational Allergy, Vol 9, Iss 1, Pp 1-8 (2019)
Druh dokumentu:	article
ISSN:	2045-7022
DOI:	10.1186/s13601-019-0272-9
Popis:	Abstract Background Hereditary angioedema with C1 inhibitor deficiency (C1-INH-HAE) is characterized by recurrent swelling in subcutaneous or submucosal tissues. Symptoms often begin by age 5–11 years and worsen during puberty, but attacks can occur at any age and recur throughout life. Disease course in elderly patients is rarely reported. Methods The Icatibant Outcome Survey (IOS) is an observational study evaluating the safety, tolerability, and efficacy of icatibant. We conducted descriptive analyses in younger (age
Databáze:	Directory of Open Access Journals
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