The cardiopulmonary bypass and cancer dissemination puzzle

Autor: Paulo Roberto Barbosa Évora, Agnes Afrodite Sumarelli Albuquerque, Tales Rubens de Nadai, Enio David Mente, Ajith Kumar Sankarankuty, Orlando Castro-e-Silva
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Acta Cirúrgica Brasileira, Vol 33, Iss 11, Pp 1037-1042 (2018)
Druh dokumentu: article
ISSN: 0102-8650
DOI: 10.1590/s0102-865020180110000010
Popis: Abstract Early cancer diagnosis, new therapies that increased survival of patients, besides the increasingly elderly population are some factors would be associated with possible cancer dissemination in patients under cardiopulmonary bypass (CPB) cardiac surgery. Also, the benefits, and risks, regarding long-term survival, have not yet been established. Therefore, cardiac surgery morbimortality may be superior in patients with cancer disease. Also, immunologic and inflammatory changes secondary to CPB can also increase tumor recurrence. After a brief introduction and CPB immunologic the two main topic subjects included: 1) Combined heart surgery and lung resection and; 2) Possible influence of neoplasia type. After observing the relative literature scarcity, we keep the opinion that “CPB has a modest association with cancer progression” and that “CPB and cancer dissemination should be a logical but unlikely association.”
Databáze: Directory of Open Access Journals