| Autor: |
Nathan K Ho, Aleah C Henry, Kathene Johnson-Henry, Philip M Sherman |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Canadian Journal of Gastroenterology, Vol 27, Iss 5, Pp 281-285 (2013) |
| Druh dokumentu: |
article |
| ISSN: |
0835-7900 |
| DOI: |
10.1155/2013/138673 |
| Popis: |
Enterohemorrhagic Escherichia coli serotype O157:H7 is a food- and waterborne pathogen that causes significant morbidity and mortality in both developing and industrialized nations. The present review focuses on the history, epidemiology and evolution of the pathogen; provides a mechanistic overview of major virulence factors (including Shiga toxins, locus of enterocyte effacement pathogenicity island and pO157 plasmid); discusses host immune responses to infection; considers available animal models; and provides an overview of current and potential future management considerations. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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