Arginine and its metabolites stimulate proliferation, differentiation, and physiological function of porcine trophoblast cells through β-catenin and mTOR pathways

Autor:	Shuai Li, Xiangyang Ye, Xiaolu Wen, Xuefen Yang, Li Wang, Kaiguo Gao, Hao Xiao, Zongyong Jiang
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Arginine Porcine trophoblast cells Cell proliferation Veterinary medicine SF600-1100
Zdroj:	BMC Veterinary Research, Vol 20, Iss 1, Pp 1-12 (2024)
Druh dokumentu:	article
ISSN:	1746-6148
DOI:	10.1186/s12917-024-04023-w
Popis:	Abstract Arginine, which is metabolized into ornithine, proline, and nitric oxide, plays an important role in embryonic development. The present study was conducted to investigate the molecular mechanism of arginine in proliferation, differentiation, and physiological function of porcine trophoblast cells (pTr2) through metabolic pathways. The results showed that arginine significantly increased cell viability (P
Databáze:	Directory of Open Access Journals
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