Blood indexes of nitrite toxicosis in dairy cows

Autor: B. Stefanon, G. Stradaioli, S. Sgorlon
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Italian Journal of Animal Science, Vol 2, Iss 1S, Pp 166-168 (2011)
Druh dokumentu: article
ISSN: 1594-4077
1828-051X
DOI: 10.4081/ijas.2003.s1.166
Popis: Nitrate (NO_ 3) and nitrite (NO_ 2) can be ingested with water and feeds and NO_ 2 can be produced from NO_ 3 by rumen and intestinal microbes. Moreover,NO_ 3 and NO_ 2 are endogenously produced by cells of various tissues from nitric oxide (NO) and arginine (Passi, 2000). Toxicity of NO_ 3 is casued by the reduction to NO_ 2 in the rumen environment. This ion competes with superoxide for hemoglobin (Doyle et al., 1982), producing methemoglobin (MtHb), which does not carry oxygen. The reaction is reversible, but the transient hypoxia can be exacerbated if the amount of ingested nitrates is high, causing fall of blood pressure and increase of heart rate........
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