On the Famous Traditional Chinese Medicine 'Fu Zi': Discovery, Research, and Development of Cardioactive Constituent Mesaconine

Autor: Feng-Peng Wang, Ruo-Bing Chao
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Natural Products and Bioprospecting, Vol 11, Iss 1, Pp 15-20 (2020)
Druh dokumentu: article
ISSN: 2192-2195
2192-2209
DOI: 10.1007/s13659-020-00266-w
Popis: Abstract This review summarizes the process of the discovery, research, and development of a cardioactive component, mesaconine, from the lateral roots of Aconitum carmichaelii (“Fu Zi”). To date, pre-clinical showed that mesaconine is a novel type of cardiotonic lead drug with relatively high potency, low toxicity, and a new mechanism. Graphic Abstract
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