Autor: |
Berkan Armağan, Ebru Atalar, Bahar Özdemir, Özlem Karakaş, Esra Kayacan Erdoğan, Serdar Can Güven, İsmail Doğan, Orhan Küçükşahin, Abdulsamet Erden |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Gülhane Tıp Dergisi, Vol 64, Iss 4, Pp 301-306 (2022) |
Druh dokumentu: |
article |
ISSN: |
2146-8052 |
DOI: |
10.4274/gulhane.galenos.2022.93723 |
Popis: |
Aims:Rheumatological disease flares may occur after many infections. However, our knowledge of the post-Coronavirus disease-2019 (COVID-19) axial spondyloarthritis (SpA) flares and related factors is limited.Methods:We retrospectively assessed the axial SpA patients who had COVID-19. Demographic and clinical data were collected from the medical records. The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) was applied via telephone for pre- and post-COVID-19 SpA symptoms. An increase of ≥2 points in the BASDAI score or any new extra-articular manifestations were defined as SpA flares and SpA patients were grouped as flares and no-flare. Factors predicting SpA flare were also analyzed.Results:A total of 48 axial SpA patients were included in the study [age, mean±standard deviation (SD): 42.3±8.6 years; male: 65%]. Post-COVID-19 SpA flare was identified in 19 patients (40%), and new extra-articular manifestations were recorded in 6 patients (13%). Although the diagnosis of inflammatory bowel disease was more common in the flare group, the difference was not significant compared with that of the no-flare group. Other features of SpA and COVID-19 disease severity were similar between the flare and no-flare groups. In the flare group, the frequency of back pain (84% vs. 62%, p=0.091) and diarrhea (53% vs. 28%, p=0.080), and headache (84% vs. 52%, p=0.021) were higher than the no-flare group. No risk factor for a post-COVID-19 SpA flare could be identified.Conclusions:Post-COVID-19 flare was common in the axial SpA, and even new extra-articular manifestations could be reported. Although some clinical manifestations of COVID-19 were more common in patients with a flare, any predictive factor could not be identified among the study variables. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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