| Autor: |
Su Lan Yang, Adiratna Mat Ripen, Jen Ven Lee, Karina Koh, Chia How Yen, Avinash Kumar Chand, Nur Aisyah Binti Abdul Rahim, Varaalakshmy Gokilavanan, Nik Nur Eliza Binti Mohamed, Raj Kumar A/L Sevalingam, Kalaiarasu M. Peariasamy |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
International Journal of Infectious Diseases, Vol 128, Iss , Pp 98-101 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1201-9712 |
| DOI: |
10.1016/j.ijid.2022.12.025 |
| Popis: |
Objectives: To study the incidence of Omicron infections in Malaysia and the exposures that could reduce the hazard of attaining Omicron infection. Methods: We used a multicenter, prospective cohort to study 482 healthcare workers vaccinated with two and three doses of BNT162b2 for SARS-CoV-2 infection during the Omicron-dominant period in Malaysia. Results: Between January 31 and July 31, 2022, the cumulative incidence was 44.6% (95% CI 40.2-49.1%), and the incidence rate was 3.33 (95% CI 2.91-3.80) per 1000 person-days. Our study found that protection against Omicron infection was significantly higher for persons with previous SARS-CoV-2 infection (hazard ratio [HR] 0.41, 95% CI 0.27-0.62) and persons with a more recent immunity event (90 days, HR 3.82, 95%CI 1.34-10.90) from the beginning of the Omicron period. Conclusion: Pre-Omicron natural infection and a recent immunity event protect against future Omicron infections. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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