Sex and Transcatheter Aortic Valve Implantation: Impact of Female Sex on Clinical Outcomes

Autor: Alessandra Laricchia, Barbara Bellini, Vittorio Romano, Saud Khawaja, Matteo Montorfano, Alaide Chieffo
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Interventional Cardiology: Reviews, Research, Resources, Vol 14, Iss 3, Pp 137-141 (2019)
Druh dokumentu: article
ISSN: 1756-1485
1756-1477
DOI: 10.15420/icr.2019.07.R1
Popis: Transcatheter aortic valve implantation (TAVI) has emerged as an alternative treatment for severe symptomatic aortic stenosis in patients who are not suitable for surgery or are at high surgical risk. Approximately 50% of patients undergoing TAVI are female and this is reflected by a higher inclusion rate of women in TAVI trials. However, women undergoing TAVI have different baseline clinical characteristics in comparison to men, with fewer comorbidities and a more preserved left ventricular ejection fraction. This translates into favourable outcomes after TAVI, despite a higher rate of peri-procedural complications. This article discusses gender differences in terms of presentation, procedural characteristics and post-procedural results in patients with aortic stenosis undergoing TAVI, with particular focus on possible sex-specific factors affecting outcome.
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