Stop using the flotation technique and start weighing salbutamol pressurised metered-dose inhalers without dose counters

Autor: Ermindo R. Di Paolo, Stéphanie Spaggiari, André Pannatier, Farshid Sadeghipour, Isabelle Rochat, Gaudenz M Hafen
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Swiss Medical Weekly, Vol 145, Iss 3132 (2015)
Druh dokumentu: article
ISSN: 1424-3997
DOI: 10.4414/smw.2015.14162
Popis: Salbutamol pressurised metered-dose inhalers (pMDIs) are not equipped with dose counters outside the USA. The aim of this study was to describe a simple reproducible method for determining the number of doses remaining in a pMDI based on scale weight. With a laboratory scale, the mean weight of the canisters was 28.61 ± 0.10 g after priming and 14.84 ± 0.23 g after 200 puffs. Similar results were obtained with two common digital scales. We recommend weighing salbutamol canisters on a common digital scale, and replacing an old pMDI with a new one when the weight falls to ≤15 g.
Databáze: Directory of Open Access Journals