Association of Length of Stay and COVID-19 in Rotational Ankle Fracture Surgery in the National COVID Cohort Collaborative (N3C)

Autor: Charles C. Pitts MD, Eli Levitt MS, David A. Patch MD, Alfredo Terrero MD, Reed Butler MD, Brent A. Ponce MD, Steven M. Theiss MD, Clay A. Spitler MD, Michael D. Johnson MD
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Foot & Ankle Orthopaedics, Vol 7 (2022)
Druh dokumentu: article
ISSN: 2473-0114
24730114
DOI: 10.1177/2473011421S00398
Popis: Category: Ankle; Trauma Introduction/Purpose: Coronavirus (COVID-19) is an emerging, rapidly evolving situation. The National COVID Cohort Collaborative (N3C) is an innovative approach to integrate real-world clinical observations into a harmonized database. To investigate the outcomes of adults with ankle fracture surgery during the (COVID-19) pandemic, we had the following research question: What are the outcomes of ankle fracture patients with COVID-19 (invasive ventilation, length of stay, death)? The purpose of this abstract is to introduce the largest cohort of ankle fracture patients to date with a comparison between lab- confirmed COVID-19-positive and COVID-19-negative. Methods: A retrospective cohort of adults with ankle fracture surgery in the N3C Data Enclave. The N3C Data Enclave is an NIH-funded, secure platform through which the harmonized clinical data from electronic health records is stored ( https://covid.cd2h.org/ ). COVID-19 status was determined using a set of 55 SARS-CoV-2 polymerase chain reaction and antigen lab tests. Ankle fracture surgery was defined using SNOMED codes for 'fracture of bone' and one of the following CPT codes '27766, 27769, 27792, 27814, 27822, 27823, 27829' for 'ankle fracture surgery.' Results: A total population of 3.4 million patient records was queried in the National COVID Cohort, identifying 2,032 participants with ankle fracture surgery. The age range of the overall group was 18-98 years. Comparing COVID-19-positive to COVID-19-negative, the age (48.9 years vs 47.7 years) and gender (66.7% female vs 55.1% female) distribution of each group were comparable (both p>0.05). COVID-19-positive comprised 2.4% of the group (n=48). The length of stay was 4.7 days longer in the COVID-19-positive group (8.7 days vs 4.0 days, p
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