Gut Microbiota in Human Immunodeficiency Virus Infection

Autor: Rudi Wisaksana, Guntur Darmawan, Nenny Agustanti, Dolvy Girawan
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, Vol 20, Iss 1, Pp 38-43 (2020)
Druh dokumentu: article
ISSN: 1411-4801
2302-8181
DOI: 10.24871/201201938-43
Popis: Human microbiota, majority presents in human gastrointestinal tract, plays crucial role in body physiological functions, such as immune system. Human immunodeficiency virus (HIV) infection impairs gut barrier and alter the microbiota ecosystem, called dysbiosis. Different phase of HIV infection demonstrates different composition of gut microbiota. Antiretroviral treatment might improve the CD4 level, however, it inconsistently restore the gut ecosystem. Some studies in prebiotic and probiotic revealed the potential effect in reducing inflammation and restoring gut microbiota.
Databáze: Directory of Open Access Journals