Nasal mucocutaneous leishmaniasis (MCL) with necrotizing granulomatous inflammation inducing cytotoxic T-cell lymphoma in a male Yemeni patient

Autor: Hamdi Ibrahim, Khairy Abd El Hamid, Tarek Abd El Aziz, Ahmed Samir El bahwashy, Hamed Khattab, Basma Aaref, Essam Elsayed
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: The Egyptian Journal of Internal Medicine, Vol 35, Iss 1, Pp 1-7 (2023)
Druh dokumentu: article
ISSN: 2090-9098
DOI: 10.1186/s43162-023-00219-y
Popis: Abstract Leishmaniasis is a protozoal infection transmitted by sandfly vector; there are three main types of leishmaniasis: cutaneous leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), and visceral leishmaniasis (VL). Herein, we present a case of endonasal mucocutaneous leishmaniasis in a 34-year-old Yemeni patient who presented with disfiguring nasal swelling associated with fever, a swab from the lesion and direct microscopic examination proved to have mucocutaneous leishmaniasis; he was successfully treated with intravenous antimonial stibogluconate, 1 month after treatment biopsy from the lesion revealed cytotoxic T-cell lymphoma, the purpose is to alert the physicians and otolaryngologists to consider leishmaniasis in the differential diagnosis of nasal granulomas and also to highlight the importance of early diagnosis of cancer in survivors of cutaneous leishmaniasis, especially in areas where cutaneous leishmaniasis is still highly prevalent, as the chronic local inflammation may disfigure the face if not recognized early and adequately treated; also, early cancer diagnosis can prevent mortality
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