| Autor: |
Ali Caner Özdöver, İlknur Gündeş, Melya Pelin Kırık, Handan Haydaroğlu Şahin, Murat Sucu, Mustafa Pehlivan |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Turkish Journal of Hematology, Vol 36, Iss 1, Pp 19-24 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1308-5263 |
| DOI: |
10.4274/tjh.galenos.2018.2018.0015 |
| Popis: |
Objective: Hematopoietic stem cell transplantation (HSCT) is a choice of treatment for malignant and non-malignant diseases. After HSCT, some complications may develop in patients. Cardiac complications are particularly important. The aim of this study was to investigate whether systolic pulmonary artery pressure (PAP) is a marker for overall survival (OS) in HSCT patients. Materials and Methods: In our study, 428 HSCT patients were evaluated. Ejection fraction (EF) and PAP values were investigated during symptom-oriented echocardiography in the pre-HSCT and post-HSCT periods. Results: Pre-HSCT EF values were similar between the groups. In patients with autologous HSCT (auto-HSCT) (PAP >25 mmHg), it was found that the 5-year mortality rate was 48.6%, while in the other group (PAP 25 mmHg, while OS was 61% in the pre-auto-HSCT period with PAP values of 0.05). Conclusion: Our results suggest that pre-HSCT PAP value is an important risk factor for mortality and OS in patients undergoing auto-HSCT. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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