Bilateral extensive CMV retinitis in a sick child – Harbinger of severe combined immunodeficiency
| Autor: | H S Vinayaka, Tummala Sujith Kumar, G V Basavaraj, Sagar Bhattad |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Journal of Pediatric Critical Care, Vol 4, Iss 4, Pp 103-105 (2017) |
| Druh dokumentu: | article |
| ISSN: | 2349-6592 2455-7099 |
| DOI: | 10.21304/2017.0404.00220 |
| Popis: | Cytomegalovirus (CMV) retinitis is a marker of severe cellular immunodeficiency. Severe combined immunodeficiency (SCID) must be considered in infants presenting with CMV retinitis in a non-HIV setting. Severe combined immunodeficiency (SCID) is a life-threatening syndrome characterized by recurrent infections, diarrhoea, dermatitis, and failure to thrive. Clinically, most children present before the age of 3 months. Without intervention, SCID is universally fatal. SCID is considered a pediatric emergency because survival depends on expeditious hematopoietic stem cell transplantation. Cytomegalovirus (CMV) is the most common opportunistic ocular infection in children with SCID. We report a 4-month-old male infant, with extensive bilateral CMV retinitis secondary to SCID. |
| Databáze: | Directory of Open Access Journals |
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