Multilayer intensity modulated contact interventional radiotherapy (brachytherapy): Stretching the therapeutic window in skin cancer

Autor: Bruno Fionda, Elisa Placidi, Enrico Rosa, Valentina Lancellotta, Gerardina Stimato, Martina De Angeli, Francesco Giuseppe Ciardo, Patrizia Cornacchione, Frank-Andre Siebert, Luca Tagliaferri, Luca Indovina
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Contemporary Brachytherapy, Vol 15, Iss 3, Pp 220-223 (2023)
Druh dokumentu: article
ISSN: 1689-832X
2081-2841
72215887
DOI: 10.5114/jcb.2023.127837
Popis: Interventional radiotherapy (IRT, brachytherapy) is a highly effective treatment method for non-melanoma skin cancer (NMSC). Traditionally, the maximum depth of NMSC lesions considered eligible for contact IRT was 5 mm; however, following several national surveys and recent recommendations, such cut-off, lesions thicker than 5 mm may be treated by contact IRT. The use of image guidance in defining the actual depth in treating NMSC to correctly identify clinical target volume (CTV) and prevent unnecessary toxicity is of paramount importance. The aim of the paper was to describe a multilayer arrangement of catheters to treat NMSC lesions thicker than 5 mm, thus proposing an example of dynamic intensity modulated IRT, using different catheter-to-skin distance of sources to reach the best CTV coverage and maximally reduce the excess of dose to the skin.
Databáze: Directory of Open Access Journals