Neisseria meningitidis Serogroup W, Burkina Faso, 2012

Autor: Jessica R. MacNeil, Isaïe Medah, Daouda Koussoubé, Ryan T. Novak, Amanda C. Cohn, Fabien V.K. Diomandé, Denis Yelbeogo, Jean Ludovic Kambou, Tiga F. Tarbangdo, Rasmata Ouédraogo-Traoré, Lassana Sangaré, Cynthia Hatcher, Jeni Vuong, Leonard W. Mayer, Mamoudou H. Djingarey, Thomas A. Clark, Nancy E. Messonnier
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 20, Iss 3, Pp 402-407 (2014)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid2003.131407
Popis: In 2010, Burkina Faso became the first country to introduce meningococcal serogroup A conjugate vaccine (PsA-TT). During 2012, Burkina Faso reported increases in Neisseria meningitidis serogroup W, raising questions about whether these cases were a natural increase in disease or resulted from serogroup replacement after PsA-TT introduction. We analyzed national surveillance data to describe the epidemiology of serogroup W and genotyped 61 serogroup W isolates. In 2012, a total of 5,807 meningitis cases were reported through enhanced surveillance, of which 2,353 (41%) were laboratory confirmed. The predominant organism identified was N. meningitidis serogroup W (62%), and all serogroup W isolates characterized belonged to clonal complex 11. Although additional years of data are needed before we can understand the epidemiology of serogroup W after PsA–TT introduction, these data suggest that serogroup W will remain a major cause of sporadic disease and has epidemic potential, underscoring the need to maintain high-quality case-based meningitis surveillance after PsA–TT introduction. Download MP3 Length: 1:40
Databáze: Directory of Open Access Journals
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