Impact of early cognitive impairment on outcome trajectory in patients with intracerebral hemorrhage

Autor: Zuo‐Qiao Li, Xiao‐Qing Bu, Jing Cheng, Lan Deng, Xin‐Ni Lv, Zi‐Jie Wang, Xiao Hu, Tian‐Nan Yang, Hao Yin, Xue‐Yun Liu, Li‐Bo Zhao, Peng Xie, Qi Li
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Annals of Clinical and Translational Neurology, Vol 11, Iss 2, Pp 368-376 (2024)
Druh dokumentu: article
ISSN: 2328-9503
DOI: 10.1002/acn3.51957
Popis: Abstract Objective To assess the prevalence and factors associated with early cognitive impairment in intracerebral hemorrhage (ICH) patients and to describe short‐term recovery trajectories among ICH patients with early cognitive impairment. Methods We prospectively enrolled ICH patients without baseline dementia in our institutions. Cognitive function was assessed using mini‐mental state examination (MMSE), and functional outcome was evaluated at discharge, 3, and 6 months after symptoms onset using the modified Rankin Scale (mRS). We used multinomial logistic regression models to investigate potential risk factors and generalized linear models to analyze the functional outcome data. Results Out of 181 patients with ICH, 167 were included in the final analysis. Early cognitive impairment occurred in 60.48% of patients with ICH. Age (odds ratio [OR] per 1‐year increase, 1.037; 95% confidence interval [CI], 1.003–1.071; p = 0.034), National Institutes of Health Stroke Scale (NIHSS) score (OR per 1‐point increase, 1.146; 95% CI, 1.065–1.233; p
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