Hyperoxia for accidental hypothermia and increased mortality: a post-hoc analysis of a multicenter prospective observational study

Autor:	Ryo Yamamoto, Jo Yoshizawa, Shuhei Takauji, Mineji Hayakawa, Junichi Sasaki
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Hyperoxemia Arterial partial pressure of oxygen Oxygen toxicity Reactive oxygen species Severe hypothermia Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Zdroj:	Critical Care, Vol 27, Iss 1, Pp 1-10 (2023)
Druh dokumentu:	article
ISSN:	1364-8535
DOI:	10.1186/s13054-023-04407-8
Popis:	Abstract Background Supraphysiologic oxygen administration causes unfavorable clinical outcomes in various diseases, including traumatic brain injury, post–cardiac arrest syndrome, and acute lung injury. Accidental hypothermia is a critical illness that reduces oxygen demands, and excessive oxygen is likely to emerge. This study aimed to determine whether hyperoxia would be associated with increased mortality in patients with accidental hypothermia. Methods A post-hoc analysis of a nationwide multicenter prospective observational study (ICE-CRASH study) on patients with accidental hypothermia admitted in 2019–2022 was conducted. Adult patients without cardiac arrest whose core body temperature was
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/d71ea24f64ef47e29870d4916941c774 Zobrazit plný text záznamu Full text from SpringerLink View record in DOAJ