Serological characteristics of HBsAg positive/HBV DNA non-reactive blood donors
Autor: | Yuanyuan JING, Yun FAN, Yan GUO, Wenjuan ZHANG, Yong DUAN, Na FENG |
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Jazyk: | čínština |
Rok vydání: | 2024 |
Předmět: | |
Zdroj: | Zhongguo shuxue zazhi, Vol 37, Iss 4, Pp 412-416 (2024) |
Druh dokumentu: | article |
ISSN: | 1004-549X 1004-549x |
DOI: | 10.13303/j.cjbt.issn.1004-549x.2024.04.007&lang=en |
Popis: | Objective To explore the distribution of serological markers related to samples whose serological test results were inconsistent with HBV DNA test results among voluntary blood donors in Xi′an. Methods A total of 71 HBsAg ELISA positive and NAT non-reactive (ELISA+ /NAT-)blood samples were collected from Shaanxi Blood Center from November 1, 2022 to April 30, 2023. The serological markers of hepatitis B were detected by electrochemiluminescence method, and the HBV S region and C region gene fragments were amplified by nested-PCR. Results The positive rate of nested-PCR in double ELISA+ /NAT- group(n=30) was statistically higher than that of ELISA+ /NAT- group(n=41)(60% vs 24.4%, P |
Databáze: | Directory of Open Access Journals |
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